Teaching plan for the course unit

 

 

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General information

 

Course unit name: Nanoscale Diagnostic Systems

Course unit code: 571431

Academic year: 2021-2022

Coordinator: Annalisa Calo

Department: Department of Electronic and Biomedical Engineering

Credits: 2,5

Single program: S

 

 

Estimated learning time

Total number of hours 62.5

 

Face-to-face and/or online activities

30

 

-  Lecture

Face-to-face and online

 

30

Supervised project

12.5

Independent learning

20

 

 

Recommendations

 


Requisites

571412 - Nanobiotecnologia (Recommended)

 

 

Competences to be gained during study

 

Basic competences

— Capacity to apply the acquired knowledge to problem-solving in new or relatively unknown environments within broader (or multidisciplinary) contexts related to the field of study.

— Capacity to integrate knowledge and tackle the complexity of formulating judgments based on incomplete or limited information, taking due consideration of the social and ethical responsibilities involved in applying knowledge and making judgments.

— Capacity to communicate conclusions, judgments and the grounds on which they have been reached to specialist and non-specialist audiences in a clear and unambiguous manner.

 

General competences

— Capacity to work independently, manage time and projects effectively, and acquire specific knowledge in order to gain entrance to doctoral programmes in nanoscience and nanotechnology.

— Initiative in the development of innovative work methods that can contribute to scientific and technological development in nanoscience and nanotechnology.

 

Specific competences

— Capacity to recognize technological advances and current problems in the domain of nanotechnology as an interdisciplinary science.

— Ability to use calculation tools and theoretical models to advance the understanding of basic properties and phenomena, and to model and predict the behaviour of nanosystems.

— Ability to perform research and development tasks in relation to new nanostructured materials and nanodevices with innovative functionalities and potential applications in biotechnology, pharmacotherapy, information processing and storage, and improved energy use.

— Abilities and skills in the field of nanotechnology to establish future areas of research, development and production in companies associated with the field.

 

 

 

 

Learning objectives

 

Referring to knowledge

— Acquire a knowledge of general basic nanomedicine and medical diagnostic systems providing a critical and realistic overview of the current state of diagnostic systems with parallel application within nanomedicine and vice versa.

 

— Acquire an understanding of the improvements in these devices by considering alternative diagnostic devices with improved characteristics employing nanoscale materials and miniaturisation of the technology resulting in cost-effectivity and portability.

 

Referring to abilities, skills

— Understand why nanosystems or nanotechnology platforms are cutting edge tools for novel development of medical diagnostic nanosystems.

 

Referring to attitudes, values and norms

— Acquire knowledge and skills in an interdisciplinary field not compromising social and ethical responsibilities.

 

 

Teaching blocks

 

Overview on biosensors

*  *  Fundamental principles

*  Structures of biosensors

*  Classification of detection system

*  Principles of microfluidics

Introduction to nanomedicine and nanodiagnostics

*  Principles and areas of nanomedicine, current level of development and state-of-the-art nanodiagnostic systems

In-vitro nanodiagnostics

*  *  Lateral flow essays enhanced with nanoparticles

*  DNA microarrays

*  Bio-bar codes

*  Nanowires and nanopores

*  Cantilever arrays

*  Atomic force microscopy for nanodiagnostics 

*  Future: lab-on-a-chip

In-vivo nanodiagnostics

*  *  Advanced nanoimaging techniques

*  Magnetic-nanoparticle-enhanced NMR

*  Implantable devices

*  Future: quantum dots, gold nanoparticles (NP) for CT

 

 

Teaching methods and general organization

 

• Magistral lectures (presencial)

• Discussion sessions

• Assignments

 

 

Official assessment of learning outcomes

 

Continuous assessment
 

The final grade is calculated as follows:

• Assignments and Participation (30%)

• Written report on the state-of-the-art of a nanosystem described during the course (30%)

• Oral presentation on selected topics (40%)

• Attendance to 80% of the course is mandatory.

Students are entitled to repeat assessment provided that they have completed all mandatory activities. The corresponding final exam corresponds to 100% of the final grade.

 

Examination-based assessment

Student who wish to opt for the unique assessment must inform the coordinator of the subject and officially notify the coordinator of the master’s degree within the established deadlines. The course mandatory activities (attendance to the course) must be completed to be entitled to take the exam. Unique assessment will consist in a oral or written exam with multiple choice and open questions on the main topics of the course.