Teaching plan for the course unit



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General information


Course unit name: Molecular Principles and Research in Metabolism and Endocrinology

Course unit code: 569891

Academic year: 2021-2022

Coordinator: Pedro Fermin Marrero Gonzalez

Department: Faculty of Medicine

Credits: 3

Single program: No definit



Estimated learning time

Total number of hours 75


Face-to-face and/or online activities



-  Lecture

Face-to-face and online




-  Document study

Face-to-face and online




-  Seminar

Face-to-face and online




-  Other class types

Face-to-face and online







A basic knowledge of metabolism and hormonal signalling is required to properly follow this course.



Learning objectives


Referring to knowledge

— Understand the signalling pathways that affect metabolism and the role that metabolites have in the control of gene expression.

— Understand the implications of procedures studied in processes such as obesity, type-2 diabetes or atherosclerosis.


Referring to abilities, skills

— Understand specialized articles in the field of metabolism and endocrinology.

— Develop a critical sensibility that allows students to evaluate the scientific information consulted.



Teaching blocks


1. Metabolic pathways

1.1. Metabolic pathways, tissues and key molecules

1.2. Hormones, signalling pathways and signal molecules

2. Gene expression

2.1. Metabolic control of gene expression

3. Obesity and metabolism

3.1. Metabolism and disease: obesity and control of food intake

4. Diabetes and metabolism

4.1. Definition, natural history and diagnoses of diabetes

4.2. Insulin signalling pathway

4.3. Type 2 diabetes mellitus and adipose tissue

5. Cardiovascular disease and metabolism

5.1. Metabolism and cardiovascular disease

6. Cancer cell metabolism

6.1. Metabolism and cancer

7. Inborn errors of metabolism

7.1. Metabolic inborn errors



Teaching methods and general organization


Classroom activities

— Lectures taught by specialists in each subject

— Seminars of specific aspects taught by expert researchers

Distance activities

— Students complete individual activities via the Virtual Campus, including the reading of scientific articles and completion of tests to assess their understanding.



Official assessment of learning outcomes


The assessment criteria of this course evaluates the acquisition of the objectives for the subject.

Continuous assessment consists of:

• Three online questionnaires, to evaluate the understanding of scientific articles (30% of the final grade)

• Written final examination (online), to evaluate the capacity for synthesis (60% of the final grade)

• Class attendance and participation (10% of the final grade).