Teaching plan for the course unit

 

 

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General information

 

Course unit name: Molecular and Cell Principles and Physiopathology of Diabetes

Course unit code: 569897

Academic year: 2021-2022

Coordinator: Manuel Vazquez Carrera

Department: Faculty of Medicine

Credits: 3

Single program: No definit

 

 

Estimated learning time

Total number of hours 75

 

Face-to-face and/or online activities

32

 

-  Lecture

Face-to-face and online

 

18

 

-  Group tutorial

Face-to-face and online

 

4

 

-  Document study

Face-to-face and online

 

2

 

-  Student presentation and discussion

Face-to-face and online

 

2

 

-  Seminar

Face-to-face and online

 

6

Supervised project

21

Independent learning

22

 

 

Recommendations

 

Language
The course is taught in English, and the articles and class materials are written in English as well. Students are expected to have a level of proficiency in English that enables them to understand scientific articles, and basic oral (conversational) and writing skills to engage in course discussions or make oral presentations of scientific literature.

Previous knowledge
Classes require an advanced level, with an emphasis on the analysis of biological processes including molecular, biochemical, cellular and therapeutic perspectives. Students are expected to demonstrate a knowledge and understanding of cell biology, molecular genetics, biochemistry and pharmacology equivalent to the level achieved with a university degree in Biology, Pharmacy, Biochemistry or Medicine.

 

 

Competences to be gained during study

 

General competences

— Ability to acquire, critically process and communicate specific information and ability to propose and discuss hypotheses.

— Ability to outline and design experimental, theoretical or numerical approaches to solve specific questions.


Specific competences

— Ability to describe major mechanisms, networks and pathways involved in the pathophysiology of diabetes.

 

 

 

 

Learning objectives

 

Referring to knowledge

Referring to knowledge

— Understand the cellular and molecular mechanisms involved in the pathophysiology of diabetes in order to identify the potential pharmacological targets in its treatment.

Referring to skills, abilities

— Acquire the ability to communicate scientific information both orally and in written form.
— Acquire researching skills for scientific information and an ability to organize it. Learn to integrate and connect this information.
— Acquire the ability to reason, deduct and critically analyse scientific research.

Referring to attitudes, values and norms

— Promote work in cooperative groups.
— Promote leadership and decision making.
— Promote self-criticism as a working tool and constructive criticism in relation to your partners.

 

 

Teaching blocks

 

1. Contents of the course

*  1. Definition, natural history and diagnosis of diabetes
2. Biology and physiology of the beta cell
3. Insulin signalling pathways
4. Monogenic and mitochondrial diabetes
5. Type 1 diabetes mellitus; Etiology and immunology
6. Type 2 diabetes mellitus and pancreas
7. Type 2 diabetes and adipose tissue
8. Neuroendocrine factors involved in the development of insulin resistance
9. Inflammation and insulin resistance
10. Animal and cellular models of diabetes mellitus

 

 

Teaching methods and general organization

 

This course is part of a master’s degree with a clear orientation towards PhD studies. The course consists of a combination of introductory lectures and presentations by students. Students are understood to have different experience and background. In addition, students are asked to analyse and present a seminar based on one published article assigned in advance. Students are expected to actively participate in all sessions by asking questions. Active contribution is acknowledged in the final grade.

 

 

Official assessment of learning outcomes

 

General criteria
— Attendance and participation in the discussion of scientific papers: 20% of the final grade.
— Individual contribution to the presentation of a research article (small group work): 80% of the final grade.

Specific criteria
The specific criteria will be explained on the first day of class.

 

Examination-based assessment

General criteria
— Attendance and participation in the discussion of scientific papers: 20% of the final grade.
— Individual contribution to the presentation of a research article (small group work): 80% of the final grade. 

Specific criteria
The specific criteria will be explained on the first day of class.

 

 

Reading and study resources

Consulteu la disponibilitat a CERCABIB

Book

The main sources of bibliography are reviews on specific topics and selected original research articles. Comprehensive electronic resources and basic textbooks recommended:

• Sociedad Española de Diabetes (SED)

• European Society for the Study of Diabetes (EASD)

• American Diabetes Association (ADA)

• Type 2 Diabetes Mellitus. Manuel Serrano Ríos y José A. Gutiérrez Fuentes. Elsevier. Biblioteca Fundación Lilly (free).