Teaching plan for the course unit



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General information


Course unit name: Arteriosclerosis, Dyslipidemia and Cardiovascular Disorders

Course unit code: 569899

Academic year: 2021-2022

Coordinator: Juan Carlos Laguna Egea

Department: Faculty of Medicine

Credits: 3

Single program: No definit



Estimated learning time

Total number of hours 75


Face-to-face and/or online activities



-  Lecture

Face-to-face and online



Supervised project


Independent learning




Competences to be gained during study


— Capacity to understand the main pathophysiological mechanisms that lead to the emergence of arteriosclerosis. Students must identify and understand the risk factors associated to the arteriosclerotic process and the general mechanisms through which they contribute to the development of atheromatous plaques. 

— Capacity to identify and understand cardiovascular diseases derived from arteriosclerosis, its relevance for the healthcare system and the clinical importance of risk factor control in the prevention of these diseases. 

— Capacity to apply the knowledge acquired to the resolution of practical experimental/clinical cases which stimulate the capacity to interpret data following the scientific method and promote critical analysis. 

— Capacity to acquire skills in scientific information research, the assimilation of theory and practice and the transmission of information orally and in written form, through scientific language.





Learning objectives


Referring to knowledge

The general objectives are those specific to the Master’s Degree in Biomedicine. As a specific general objective for the subject, students acquire a global, integrated and consolidated knowledge of the pathophysiological mechanisms involved in arteriosclerosis and their clinical consequences as cardiovascular diseases.



Teaching blocks


1. Basic atherosclerosis: Definition, time evolution of atheromatous plaques, types of cells and signalling paths involved

2. Clinical atherosclerosis: Derived cardiovascular diseases and consequences for the healthcare system, definition of risk factor, unchangeable risk factors, changeable risk factors (smoking, obesity, diabetes and insuline resistance) and multifactor control of cardiovascular risk

3. Obesity and diabetes mellitus type 2 as risk factors for atherosclerosis and cardiovascular diseases

4. Dyslipidemias: Classification and etiopathogenic mechanisms

5. Dyslipidemias: Diagnosis and treatment

6. Hypertension: Definition, types, etiopathogenic mechanisms and derived pathologies

7. Hypertension: Treatment and consequences for the healthcare system

8. Endothelial dysfunction: Etiopathogenic mechanisms, hyperhomocysteinemia, and causes and consequences

9. Unconventional risk factors: Epidemiology and diagnostic uses

10. Dyslipidemias: Control through diet

11. Dyslipidemias and drugs: Molecular targets of lipid-lowering agents

12. Products in clinical research phase for the control of hypercholesterolemia and diabetic dyslipidemia



Teaching methods and general organization


Theory sessions. Theory sessions are lectures where the teaching staff present the corresponding topic using available audiovisual media. In any case, given the reduced number of students, maximum exchange of ideas and debate between the lecturer and students is promoted. 

Seminars. This block uses methodological techniques aiming at promoting individual work, providing students with autonomy and independence to build their own learning process and supporting this task through intensive tutorial sessions. Besides, the capacity for logical reasoning and constructive criticism are promoted through debate seminars. More specifically, research seminars have the following characteristics: 

— Students must present an oral commentary on a research article / clinical case allocated by the lecturer on the date established; a week before the oral presentation, a synthetic abstract of the article must be presented to the rest of the class and once the oral presentation is concluded, question time is open for students and the lecturers. 

— The commentary of the article or clinical case is a 15-30 minute oral presentation through which students, with the support of the board and audiovisual material such as transparencies or slides, provides an introduction to the topic, comments the results, the most important techniques used to obtain these results and the real consequences of these results in the context of the topic under study. Lecturers particularly promote that students show a critical personal vision on the research presented. 

— Students who do not complete the presentation must read the abstract of the article presented and once the presentation has been concluded must actively participate during the question time.



Official assessment of learning outcomes


— Class attendance and participation. 

— Oral presentation.