Teaching plan for the course unit (Short version)
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General information

 

Course unit name: Cancer Genetics

Course unit code: 568597

Academic year: 2021-2022

Coordinator: Araceli Rosa de la Cruz

Department: Faculty of Biology

Credits: 2,5

Single program: S

Estimated learning time

Total number of hours 62.5

 

Face-to-face and/or online activities

16

	-  Lecture	Face-to-face		11
	-  Laboratory session	Face-to-face		2
	-  Seminar	Face-to-face		3

Supervised project

16.5

Independent learning

30

Learning objectives

Referring to knowledge — Identify genomic instability as a characteristic of most cancer cells and explain the reasons for this instability. — Explain the genetics of hematologic neoplasia and its importance in diagnosis, prognosis and monitoring. — Explain the genetics of solid tumours. — Use specific methods to analyse gene expression in cancer cells.

 

 

Teaching blocks

 

1. The genomic instability of cancer cells. Telomere dysfunction and chromosome instability.

2. Genetics of hematologic neoplasia

*  Examples of acute leukemia (acute lymphoblastic leukemia) and chronic leukemia (chronic lymphocytic leukemia)

 

3. Genetics of epithelial–mesenchymal transition. Colorectal cancer.

4. Whole-genome, transcriptome and methylome analysis of cancer cells

5. Observation and assessment of the most common molecular alterations in leukemia using G-banding and fluorescence in situ hybridisation (FISH)

*  Note that the total completion of this content may be subject to official COVID-19 restrictions.